FORMULATION AND EVALUATION OF POMEGRANATE PEEL LOZENGES FOR MDR
Keywords:
Pomegranate peel, Multi Drug Resistance, Antimicrobial Activity, Replica plate, Mutant Bacteria, Cytoplasmic membrane disruption.Abstract
The pomegranate fruit's (Punica granatum) outer skin is the source of pomegranate peel extract (PPE). Thanks to its scientifically proven antibacterial, antioxidant, anticancer, antiulcer, and anti-inflammatory qualities, this extract has become more and more popular. This review concentrates on PPE's antibacterial efficacy against viruses, fungi, bacteria, and parasites that are resistant to many drugs. The serial dilution method and the cup plate method were used to test PSE's antibacterial activity. According to the findings, PPE exhibits a broad range of antibacterial properties against a variety of microorganisms, such as viruses (S. aureus, E. coli, K. pneumoniae, Salmonella, Salmonella enterica, P. aeruginosa, S. marcescens, Brucella spp., and R. glutinis), fungi, and mold (F. sambucinum, P. digitatum, Saccharomyces cerevisiae, Monilinialaxa, M. fructigena,B. coagulans, B. cereus, and B. subtilis).
